CANCER CELLS EVOLVE,
SO DOES OUR SCIENCE

Cancer cells evolve continuously and co-opt the genomic and metabolic machinery of the tumor micro-environment to confer itself survival & proliferation advantages. These mechanisms employed by cancer cells, known as the ‘hallmarks of cancer’ are key to stopping cancer in its tracks.

At Incozen, our philosophy is to employ a similar a multi-pronged approach, as used by cancer cells, i.e., modulate two or more of its hallmark mechanisms simultaneously in order to vanquish cancer. This approach guides our choice of molecular targets and the pipeline of novel cancer medicines we are developing.

OUR SCIENCE AIMED AT THE HALLMARKS OF CANCER

Our Pipeline

  • Pipeline of novel, targeted, orally active agents with differentiated efficacy & safety for the treatment of hematological cancers
  • Providing therapeutic options for refractory and relapsing patients (including genetically characterized variants) alone or in combination with standard of care

About Us

Publications

Pooled Safety Analysis and Efficacy of Tenalisib (RP6530), a PI3K δ/ γ Inhibitor in Patients with Relapsed/Refractory Lymphoid Malignancies

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Umbralisib, a novel PI3Kδ and casein kinase-1ε inhibitor, in relapsed or refractory chronic lymphocytic leukaemia and lymphoma: an open-label, phase 1, dose-escalation, first-in-human study

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Addition of RP6530, a dual PI3Kδ/γ inhibitor, accentuates Romidepsin activity in NHL cells in vitro

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Safety and Anti-Tumour Activity of Tenalisib (RP6530), a Dual PI3K δ/γ Inhibitor, in Relapsed/Refractory T-Cell Lymphoma: Updated Results from the Dose Expansion Cohort of an on-Going Phase I/Ib Study

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Antitumor activity of RP4010, a novel small-molecule inhibitor of the calcium release-activated calcium (CRAC) channel pathway

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Store-operated calcium signaling is an effective therapeutic target in Acute Myeloid Leukemia (AML)

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Partner With Us

Our approach to partnering is simple and yet effective. We are looking to collaborate with partners having synergistic capabilities and programs. Our successful track record of partnerships with the likes of TG Therapeutics, Novartis etc., bear testimony to our win-win approach.

We have an affiliate entities & offices located across US, EU and India to facilitate our collaborative approach to a developing & commercializing a globally competitive pipeline.

Contact Us